#Id: 6439
#Unit 8. Inheritance Biology
Restriction Fragment length Polymorphism (RFLP)
RFLP is generated by the presence and absence of a recognition site for the same restriction endonuclease in the same region of a chromosome from the different individuals of a species.
result, the concerned restriction enzyme produces fragments of different lengths
These differences are detected by gel electrophoresis combined with hybridization with a labelled (usually, radiolabelled) probe specific for that chromosome region.