They supposed that such mutant forms constituted new species and thus believed that natural selection was not necessary to account for the origin of species. The last influential mutationist was Richard Goldschmidt

TLS Online TPP Program

#Id: 2671

#Unit 7. System Physiology – Animal

Paracellular reabsorption of cations causes slight positive charge of the tubular lumen relative to the interstitial fluid.

TLS Online TPP Program

#Id: 2672

#Unit 7. System Physiology – Animal

A slight backleak of potassium ions into the lumen, creating a positive charge of about +8 millivolts in the tubular lumen.

TLS Online TPP Program

#Id: 2673

#Unit 7. System Physiology – Animal

Positive charge forces cations such as Mg++ and Ca++ to diffuse from the tubular lumen through the paracellular space and into the interstitial fluid.

TLS Online TPP Program

#Id: 5527

#Unit 7. System Physiology – Animal

In early proximal convoluted tubule sodium is reabsorbed by co-transport along with glucose, amino acids, & other solutes.

TLS Online TPP Program

#Id: 5528

#Unit 7. System Physiology – Animal

Late proximal tubule reabsorbs primarily NaCl

TLS Online TPP Program

#Id: 5529

#Unit 7. System Physiology – Animal

In late proximal convoluted tubule High tubular fluid Cl− concentration is the driving force for reabsorption