Constitutively active Ras proteins (RasD) 

Replacement of the normal glycine 12 with any other amino acid (except proline) blocks the functional binding of GAP proteins and in essence “locks” Ras in the active GTP-bound state.

TLS Online TPP Program

#Id: 4805

#Unit 13. Methods in Biology

Quartile deviation

TLS Online TPP Program

#Id: 867

#Unit 13. Methods in Biology

Size of the primer negatively affects the efficiency of PCR.

TLS Online TPP Program

#Id: 6639

#Unit 8. Inheritance Biology

Coefficient of coincidence  Ratio of observed double crossovers to expected double crossovers.

TLS Online TPP Program

#Id: 9459

#Unit 4. Cell Communication and Cell Signaling

Ligand binding triggers a conformational change in the JAKs & they phosphorylate each other on a critical tyrosine in the activation loop which greatly enhances kinase activity

TLS Online TPP Program

#Id: 4449

#Unit 13. Methods in Biology

Electron microscopy under optimal conditions provides, a resolution of 0.10 nm wavelength.