Constitutively active Raf kinase

a glutamic acid substitution for the valine at position 600

TLS Online TPP Program

#Id: 8262

#Unit 1. Molecules and their Interaction Relevant to Biology

Even though these two atoms are interacting with each other, their dipoles may still fluctuate. However, they must fluctuate in synchrony in order to maintain their dipoles and stay interacted with each other. Result of synchronizing fluctuation of dipoles:

TLS Online TPP Program

#Id: 8263

#Unit 1. Molecules and their Interaction Relevant to Biology

Spontaneous Dipole-Induced Dipole Interaction

Spontaneous dipole-induced dipole interactions are also known as dispersion or London forces

TLS Online TPP Program

#Id: 8264

#Unit 1. Molecules and their Interaction Relevant to Biology

Dispersion or London forces are large networks of intermolecular forces between nonpolar and non-charged molecules and atoms (i.e. alkanes, noble gases, and halogens). 

TLS Online TPP Program

#Id: 8265

#Unit 1. Molecules and their Interaction Relevant to Biology

Molecules that have induced dipoles may also induce neighbouring molecules to have dipole moments, so a large network of induced dipole-induced dipole interactions may exist.

TLS Online TPP Program

#Id: 8266

#Unit 1. Molecules and their Interaction Relevant to Biology

Potential energy of an induced dipole-induced dipole interaction depends on first ionization energy of atom creating permanent dipole.

TLS Online TPP Program

#Id: 8267

#Unit 1. Molecules and their Interaction Relevant to Biology