Insulin receptor activates the PI-3 kinase/PKB pathway

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#Unit 4. Cell Communication and Cell Signaling

Antigen pieces are held within the binding groove of a cell surface protein called the major histocompatibility complex (MHC) molecule which recognized by T cell

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#Unit 4. Cell Communication and Cell Signaling

Class I MHC, glycoproteins expressed on the surface of nearly all nucleated cells; the major function of the class I is presentation of endogenous peptide antigens to CD8+ T cells.

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#Unit 4. Cell Communication and Cell Signaling

Daudi tumor cells, which are unable to synthesize β 2-microglobulin. 

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#Unit 4. Cell Communication and Cell Signaling

Class II MHC glycoproteins expressed predominantly on pAPCs, where they primarily present exogenous antigenic peptides to CD4+ T cells.

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#Unit 4. Cell Communication and Cell Signaling

Class III MHC genes encode several different proteins, some with immune functions, include the complement components C4, C2, and factor B, TNF-α and Lymphotoxin-α [TNF- α]. 

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#Id: 10370

#Unit 4. Cell Communication and Cell Signaling

HLA-G

These are present on fetal cells at the maternal-fetal interface and are credited with inhibiting rejection by maternal CD8+ T cells by protecting the fetus from identification as foreign.