Polygalacturonases (PG) secreted by the fungal hyphae interact with WAK1 on plant cell wall results in the expression of plant defense proteins, including PGIPs Chitinases, glucanases, and phytoalexins to damage the fungal hyphae

TLS Online TPP Program

#Id: 7223

#Unit 5. Developmental Biology

Thymic selection The most distinctive property of the mature T cells is that they recognize only foreign antigen combined with self-MHC molecules.

TLS Online TPP Program

#Id: 7224

#Unit 5. Developmental Biology

Two distinct selection processes are required

Positive selection, which selects for those thymocytes bearing receptors capable of binding self-MHC molecules, resulting in MHC restriction

Negative selection, which selects against thymocytes bearing high-affinity receptors for self-MHC/peptide complexes, resulting in self-tolerance.

TLS Online TPP Program

#Id: 7225

#Unit 5. Developmental Biology

TLS Online TPP Program

#Id: 7226

#Unit 5. Developmental Biology

Relationship between TCR affinity and selection

TLS Online TPP Program

#Id: 7227

#Unit 5. Developmental Biology

T-cell education

TLS Online TPP Program

#Id: 7228

#Unit 5. Developmental Biology

Superantigens

Viral or bacterial proteins that bind simultaneously to the Vβ domain of a T-cell receptor and to the α chain of a Class II MHC molecule