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TLS Online TPP Program

#Id: 9827

Mutants lacking phyA also failed to germinate in response to millisecond pulses of light, but showed a normal response to red light in the low-fluence range. Means pfr primarily receives VLFR

#Unit 6. System Physiology – Plant #Mechanisms of action of Phytochromes #Part B Pointers
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TLS Online TPP Program

#Id: 9979

#Unit 4. Cell Communication and Cell Signaling

Active Wnt signaling leads to the secretion of Notum.
TLS Online TPP Program

#Id: 9980

#Unit 4. Cell Communication and Cell Signaling

Notum, a hydrolase that associates with glypican and then cleaves off Wnt’s attached lipids in a process of deacylation or delipidation.
TLS Online TPP Program

#Id: 9981

#Unit 4. Cell Communication and Cell Signaling

Delipidation process reduces Wnt signaling, creates a negative feedback mechanism for preventing excessive Wnt signaling.
TLS Online TPP Program

#Id: 9982

#Unit 4. Cell Communication and Cell Signaling

Frizzled receptor possesses a unique hydrophobic cleft adapted to interact with lipidated Wnts, a binding conformation mimicked in Notum’s structure as well.
TLS Online TPP Program

#Id: 9983

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9984

#Unit 4. Cell Communication and Cell Signaling