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TLS Online TPP Program

#Id: 985

In the Drosophila egg, karyokinesis occurs without cytokinesis so as to create a syncytium.

#Unit 5. Developmental Biology #Drosophila #Part B Pointers
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TLS Online TPP Program

#Id: 9084

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9085

#Unit 4. Cell Communication and Cell Signaling

Subunit B recognizes and binds to specific gangliosides on the surface of intestinal epithelial cells and provides a route for subunit A to enter. 
TLS Online TPP Program

#Id: 9086

#Unit 4. Cell Communication and Cell Signaling

A1 associates with ARF6, a small G protein in host cells which are accessible only when ARF6 is in its active (GTP-bound) form. 
TLS Online TPP Program

#Id: 9087

#Unit 4. Cell Communication and Cell Signaling

Association with ARF6 activates A1, which catalyzes the transfer of ADP-ribose from NAD to the critical Arg residue in the P loop of the  subunit of Gαs. 
TLS Online TPP Program

#Id: 9088

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9089

#Unit 4. Cell Communication and Cell Signaling

ADP-ribosylation blocks the GTPase activity of Gαs and renders Gαs permanently active.