Adenoviruses and cytomegalo virus use to reduce the surface expression of class I MHC molecules, 

Measles virus and HIV, reduce levels of class II MHC molecules on the surface, 

Vaccinia virus, secreting a protein that binds to the C4b complement component.

TLS Online TPP Program

#Id: 8538

#Unit 2. Cellular Organization

Microtubules can be stabilized by side-binding microtubule associated proteins (MAPs).

TLS Online TPP Program

#Id: 8539

#Unit 2. Cellular Organization

The short (∼20 amino acid) C-terminal tails of both α- and β-tubulin that protrude from the microtubule are enriched in glutamic and aspartic acids, the surface of the microtubule possesses a net negative charge.

TLS Online TPP Program

#Id: 8540

#Unit 2. Cellular Organization

Dynein-related transport requires dynactin, that links dynein to its cargo

TLS Online TPP Program

#Id: 8572

#Unit 2. Cellular Organization

Soft keratins, or cytokeratins, are found in epithelial cells and make up the skin.

TLS Online TPP Program

#Id: 8573

#Unit 2. Cellular Organization

In all epithelia, keratin filaments associate with: Desmosomes (cell–cell contact)

Hemidesmosomes (cell–matrix contact)

TLS Online TPP Program

#Id: 8574

#Unit 2. Cellular Organization

when defective keratins are expressed in the basal cell layer of the epidermis, they produce a disorder called epidermolysis bullosa simplex