Original antigenic sin

Tendency to focus an immune attack on those structures that were present during the original.

This means that our immune systems effectively ignore the subtle changes occurring each year in pathogens

TLS Online TPP Program

#Id: 568

#Unit 2. Cellular Organization

Leaky Expression

In repressed state, an occasional transcript gets made. This happens because every so often, RNA polymerase will manage to bind the promoter in place of the Lac repressor. This leakiness encode meager level of Z, Y and A.

TLS Online TPP Program

#Id: 9451

#Unit 4. Cell Communication and Cell Signaling

The extracellular domain of cytokine receptors are constructed of two subdomains, each contains seven conserved β strands folded together

TLS Online TPP Program

#Id: 10544

#Unit 4. Cell Communication and Cell Signaling

Two BH3-only proteins, Puma and Noxa are transcriptionally induced by the p53 protein

TLS Online TPP Program

#Id: 5972

#Unit 10. Ecological Principles

Upwelling zones (where nutrients reach the surface from deeper waters) and continental shelf areas (where bottom sediments in shallow water rapidly exchange nutrients with surface waters) support greater production.

Freshwater production is highest in rivers, shallow lakes, and ponds, where nutrients are most abundant, and lowest in clear streams and deep lakes.

TLS Online TPP Program

#Id: 1428

#Unit 4. Cell Communication and Cell Signaling

TGF-β1 and TGF-β3 contain RGD motif that binds to integrins.