TLS Online TPP Program

#Question id: 1159


Cholera toxin can make you sick through overactivation of a Gs pathway even if your body stops making the ligand associated with activation of the pathway. Knowing this, which of the following CANNOT be true about cholera toxin?

#Unit 4. Cell Communication and Cell Signaling
  1. It chemically modifies the Gαs protein.

  2. Cholera toxin activates a ligand-activated G protein-coupled receptor.

  3. It prevents hydrolysis of bound GTP to GDP.

  4. It leads to continuous activation of adenylyl cyclase.