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#Question id: 1203


People who suffer from thyroid adenomas have constitutively activated G proteins in some cells of the thyroid gland. Tumor cells not only secrete copious quantities of thyroid hormones but also divide and grow excessively. Based on these observations, in what kind(s) of signal transduction pathways do the mutant G proteins participate?

#Unit 4. Cell Communication and Cell Signaling
  1. cAMP-regulated pathways

  2. MAP kinase pathways

  3. both cAMP and MAP kinase pathways

  4. neither cAMP nor MAP kinase pathways

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#Question id: 5292

#Unit 8. Inheritance Biology

A transformation experiment is performed with a donor strain that is resistant to four drugs: W, X, Y, and Z. The recipient is sensitive to all four drugs. The treated recipient population is divided up and plated on media containing various combinations of the drugs. The table below shows the results:

Drug(s) added

Number of Colonies

None

20,000

WX

76

WY

1324

WZ

1976

XY

85

XZ

69

YZ

1564

WXY

50

WXZ

62

WYZ

1354

XYZ

48

WXYZ

53

Following observation are given

A) X gene is obviously quite distant from the other three genes

B) Y gene is obviously quite distant from the other three genes

C) The Order is three closely link gene W Z Y

D) The Order is three closely link gene W X Z

Which of the following combination is correct?

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#Question id: 5293

#Unit 8. Inheritance Biology

The two strains a and b are tested for being auxotrophic for the following nutritional mutations: pyridoxine (pdx), biotin (bio), methionine (met), adenine (ade), and para-aminobenzoic acid (pab). Growth is indicated by ( + ) and lack of growth by ( - ). From these tests, what is genotype of strain a and b respectively (+ indicate prototroph while other auxotroph)? 

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#Question id: 5294

#Unit 8. Inheritance Biology

Interrupted mating experiments were performed using three different Hfr strains (1-3). The three strains have different combinations of selectable markers. The time of entry for markers for each strain is shown is shown in the table given.

Hfr 1

Phe

(5)

Trp

(35)

Met

(50)

Ala

(52)

Hfr 2

Trp

(2)

Val

(12)

His

(57)

Pro

(87)

Hfr 3

Ala

(10)

Met

(12)

Val

(37)

Phe

(57)

Using the above data, predict the correct sequence of markers on the E. coli chromosome

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#Question id: 5295

#Unit 8. Inheritance Biology

A cross is made between an Hfr that is met+ thi+ pur+ and an F-that is met- thi- pur-. Interrupted mating studies show that met+ enters the recipient last, so met+ recombinants are selected on a medium containing supplements that satisfy only the pur and thi requirements.  These recombinants are tested for the presence of the thi+ and pur+ alleles. The following numbers of individuals are found for each genotype:

A) Gene Order

I

Thi Pur  Met

II

Pur  Met  Thi

III

Pur   Thi  Met

B) Distance between Pur and Thi

IV

15.4 map unit

V

1.8 map unit

What is the following correct combination?

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#Question id: 5296

#Unit 8. Inheritance Biology

A transformation experiment is performed with a donor strain that is resistant to four drugs: A, B, C, and D. The recipient is sensitive to all four drugs. The treated recipient cell population is divided up and plated on media containing various combinations of the drugs. The table below shows the results. What is the probable order of the three tightly linked genes?  

TLS Online TPP Program

#Question id: 5297

#Unit 8. Inheritance Biology

In a generalized transduction experiment, phages are collected from an E. coli donor strain of genotype cys+ leu+thr+ and used to transduce a recipient of genotype cys_ leu_ thr_. Initially, the treated recipient population is plated on a minimal medium supplemented with leucine and threonine. Many colonies are obtained. These colonies are then replica-plated onto three different media: What is order of gene?