TLS Online TPP Program

#Question id: 1243


One form of receptor desensitization can be mediated by negative feedback involving phosphorylation of the receptor itself by a kinase activated downstream of a second messenger. The phosphorylated receptor likely:

#Unit 4. Cell Communication and Cell Signaling
  1. would be resensitized by a kinase.

  2. would activate heterotrimeric G proteins at a faster rate.

  3. would be unable to bind ligand.

  4. could be resistant to desensitization if Ser/Thr phosphatases were acting on the same receptor.