TLS Online TPP Program

#Question id: 1247


Which of the following is NOT true about the role of adapter proteins in the activation of Ras by receptor tyrosine kinases?

#Unit 4. Cell Communication and Cell Signaling
  1. Following dimerization and autophosphorylation of receptor tyrosine kinases, GRB2 and Sos proteins couple to the receptor.

  2. GRB2 and Sos proteins couple the receptor to the inactive Ras·GDP complex.

  3. GRB2 interacts with Sos via its SH3 domain.

  4. Sos acts as a GAP, which helps convert Ras·GDP to active Ras·GTP.

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TLS Online TPP Program

#Question id: 32314

#Unit 2. Cellular Organization

In cells expressing mutant versions of Sar1 or ARF that cannot hydrolyze GTP, what would be the result?
a. Vesicle coats do not form and vesicle buds pinch off.
b. The mutant proteins cannot trigger disassembly of the coat all available coat subunits eventually become permanently.
c. Unable to fuse with target membranes.
d. Blocking of coat disassembly.

TLS Online TPP Program

#Question id: 32315

#Unit 2. Cellular Organization

What triggers the release of the LDL particle from its receptor in the endosome?

TLS Online TPP Program

#Question id: 32316

#Unit 2. Cellular Organization

What phenomenon occurs when the rate of actin subunit addition is faster than nucleotide hydrolysis at the plus end but slower than nucleotide hydrolysis at the minus end?

TLS Online TPP Program

#Question id: 32317

#Unit 2. Cellular Organization

What type of interaction occurs between the β-propeller domain and the LDL-binding domain at low pH?

TLS Online TPP Program

#Question id: 32318

#Unit 1. Molecules and their Interaction Relevant to Biology

If fertilized, the egg is transformed from a single cell to a complex organism. Discuss this irreversible process in terms of the thermodynamic changes in the system as

TLS Online TPP Program

#Question id: 32319

#Unit 1. Molecules and their Interaction Relevant to Biology

The standard free-energy change for given reactions, using the equilibrium constants given for the reactions at 25 °C and pH 7.0, will be