TLS Online TPP Program

#Question id: 1247


Which of the following is NOT true about the role of adapter proteins in the activation of Ras by receptor tyrosine kinases?

#Unit 4. Cell Communication and Cell Signaling
  1. Following dimerization and autophosphorylation of receptor tyrosine kinases, GRB2 and Sos proteins couple to the receptor.

  2. GRB2 and Sos proteins couple the receptor to the inactive Ras·GDP complex.

  3. GRB2 interacts with Sos via its SH3 domain.

  4. Sos acts as a GAP, which helps convert Ras·GDP to active Ras·GTP.

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TLS Online TPP Program

#Question id: 460

#Unit 1. Molecules and their Interaction Relevant to Biology

The hydrolysis of ATP to ADP has a △G°ʹ of -30 kJ/mol. If in an E. coli cell the concentrations of ATP, ADP and inorganic phosphate are 7.90 mM, 1.04 mM and 7.9 mM, respectively, which statement is true about the hydrolysis of ATP in the cell? (Assume a temperature of 298 K. R = 8.315 J/K-mol)

TLS Online TPP Program

#Question id: 461

#Unit 1. Molecules and their Interaction Relevant to Biology

The conversion of glucose-1-phosphate to glucose-6-phosphate by the enzyme phosphoglucomutase has a △G°ʹ of -7.6 kJ/mol. Calculate the equilibrium constant for this reaction at 298 K and a pH of 7. (R = 8.315 J/K-mol)

TLS Online TPP Program

#Question id: 462

#Unit 1. Molecules and their Interaction Relevant to Biology

The formation of acetyl CoA is driven to completion by

TLS Online TPP Program

#Question id: 463

#Unit 1. Molecules and their Interaction Relevant to Biology

Thioesters are similar to oxygen esters of carboxylic acids except that

TLS Online TPP Program

#Question id: 464

#Unit 1. Molecules and their Interaction Relevant to Biology

Calculate the equilibrium constant for an oxidation-reduction reaction involving the transfer of 1 mole of electrons with DE0ʹ= 0.25 V. (R = 8.315 JK-1mol-1, F = 96.48 kJV-1mol-1, T = 298 K)

TLS Online TPP Program

#Question id: 465

#Unit 1. Molecules and their Interaction Relevant to Biology

If the standard reduction potential of a certain half-reaction is -0.30 V, which statement below is true for this half-reaction to proceed as a reduction?