TLS Online TPP Program

#Question id: 1250


Few mutants (column A) and their results (column B) are listed in the table given below:

Column A

Column B

A. Gain-of-function of Ski

I. Inhibits the ability of activated type I TGF-β receptors (RI) to phosphorylate

R-Smad proteins

B. Loss-of-function of RII receptor

II. Transcription activation induced by TGF-β and mediated by Smad complexes is shut down

C. Gain-of-function of smad-7

D. Loss-of-function of R-smad

Match the correct mutation with the observe result?

#Unit 4. Cell Communication and Cell Signaling
  1. A and D-II, B and C-I

  2. A and B-II, C and D-I

  3. A and B-I, C and D-II

  4. A and C-II, B and D-I

More Questions
TLS Online TPP Program

#Question id: 12209

#Unit 7. System Physiology – Animal

At birth, a large, well-nourished baby is found to have a plasma glucose concentration of 17 mg/Dl (normal is 80 to 100 mg/dL) and a plasma insulin concentration twice the normal value. What is the explanation for these findings?

TLS Online TPP Program

#Question id: 2903

#Unit 2. Cellular Organization

There are five known families of enzyme complexes that actively move or displace nucleosomes, hydrolyzing ATP in the process, three of which are particularly important in transcriptional activation. Which of the following statement is/are correct regarding these nucleosome remodeling complexes?

I. SWI/SNF remodels chromatin so that nucleosomes become more irregularly spaced, and stimulate the binding of transcription factors. It includes a bromodomain near the C-terminus of the active ATPase subunit, which interacts with acetylated histone tails.

II. Some members of a family, SWR1, are involved in deposition of the H2A.Z histone variant in transcriptionally inactive chromatin. 

III. NURF, a member of the ISW1 family, remodels chromatin in ways that complement and overlap the activity of SWI/SNF. These two enzyme complexes are crucial in preparing a region of chromatin for active transcription.

TLS Online TPP Program

#Question id: 4778

#Unit 8. Inheritance Biology

The following is the biochemical pathway for purple pigment production in flowers of sweet pea: A cross is made between two parents with the genotype: Aabb x AaBb. What is proportional of plant with purple pigment?

TLS Online TPP Program

#Question id: 2524

#Unit 2. Cellular Organization

Which cytoplasmic fibrils are most like the nuclear lamins?

TLS Online TPP Program

#Question id: 13214

#Unit 6. System Physiology – Plant

The stomata will open less or even remain closed on a sunny morning when