TLS Online TPP Program

#Question id: 1256


Scaffolds for MAP kinase pathways are well documented in yeast, fly, and worm cells, but their presence in mammalian cells has been difficult to demonstrate. Perhaps the best documented scaffold protein in metazoans is Ksr (kinase suppressor of Ras).

A. Ksr functions as a molecular scaffold by binding several signaling components of the MAP kinase cascade, including both MEK and MAP kinase; and thus can enhance MAP kinase activation by regulating the efficiency of these interactions.

B. Ksr function as a protein kinase which constitutive activate RTK signalling pathway.

C. Ksr function as a receptor proteins which inhibits RTK signalling pathway.

D. Ksr function as a protein phosphatase which inhibits RTK signalling pathway.

Which of the following statement is correct about Ksr?

#Unit 4. Cell Communication and Cell Signaling
  1. A and B

  2. A only

  3. C only

  4. C and D