Following statements are regarding to the phosphoinositide pathway.

A. many activated RTKs and cytokine receptors initiate phosphoinositide pathway by recruiting the enzyme phosphatidylinositol-3 kinase (PI-3 kinase) to the membrane.

B. PI-3 kinase adds a phosphate to the 3′ carbon in one of two separate phosphatidylinositol substrates, leading to formation of two phosphatidylinositol 3-phosphates: PI(3,4)P2 or I(3,4,5)P3

C. PI-3 kinase pathway can trigger cell division and prevent apoptosis, thus ensuring cell survival by the activation of PKB.

D. Activated PKB phosphorylates FOXO3a, which induces the expression of several antiapoptotic genes.

Which of the following combination is correct?

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#Question id: 11645

#Unit 7. System Physiology – Animal

Which of the following is inconsistent with the diagnosis of Graves’ disease?

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#Question id: 12809

#General Aptitude

The breadth of a rectangular hall is three-fourth of its length. If the area of the floor is 768 sq. m. then the difference between the length and breadth of the hall is:

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#Question id: 1313

#Unit 4. Cell Communication and Cell Signaling

Which type of junctions may protect a damaged cell through chemical gating?

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#Question id: 14988

#Unit 4. Cell Communication and Cell Signaling

Which of the following cells contains granules but belongs to the different lineages from granulocytes?

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#Question id: 11236

#Unit 9. Diversity of Life Forms

Which two structures play direct roles in permitting bacteria to adhere to each other, or to other surfaces?

1.  capsules

2.  endospores

3.  fimbriae

4.  plasmids

5.  flagella