Following statements are regarding to the phosphoinositide pathway.

A. many activated RTKs and cytokine receptors initiate phosphoinositide pathway by recruiting the enzyme phosphatidylinositol-3 kinase (PI-3 kinase) to the membrane.

B. PI-3 kinase adds a phosphate to the 3′ carbon in one of two separate phosphatidylinositol substrates, leading to formation of two phosphatidylinositol 3-phosphates: PI(3,4)P2 or I(3,4,5)P3

C. PI-3 kinase pathway can trigger cell division and prevent apoptosis, thus ensuring cell survival by the activation of PKB.

D. Activated PKB phosphorylates FOXO3a, which induces the expression of several antiapoptotic genes.

Which of the following combination is correct?

#Question id: 28352

#Unit 5. Developmental Biology

Which of the following protein acts as eIF4E-binding protein that specifically inhibit Oskar mRNA translation?

#Question id: 28353

#Unit 5. Developmental Biology

Before fertilization, graph representing A, B, C and D mRNA which is deposited in the oocyte by the ovarian nurse cells. Select the correct combination of these mRNAs.

#Question id: 28354

#Unit 5. Developmental Biology

The following statements were made regarding the patterning of anterior-posterior body plan of Drosophila:

A. Mutant bicoid mRNA that leads to the deletion of head and thorax

B. bicoid mutant phenotype expressed  two telson phenotype

C. the Bicoid protein activates the zygotic expression of the hunchback gene

D. the bicoid mRNA is represses the hunchback mRNA

Which one of the following options represents all correct statements as made above?

#Question id: 28355

#Unit 5. Developmental Biology

what is the function of the gene exuperantia and swallow and if it is mutated that leads to____

#Question id: 28356

#Unit 5. Developmental Biology

#Question id: 28357

#Unit 5. Developmental Biology

 what is the function of the gene tudor (tud) & oskar (osk) and if it is mutated that leads to____