Following statements are regarding to the phosphoinositide pathway.

A. many activated RTKs and cytokine receptors initiate phosphoinositide pathway by recruiting the enzyme phosphatidylinositol-3 kinase (PI-3 kinase) to the membrane.

B. PI-3 kinase adds a phosphate to the 3′ carbon in one of two separate phosphatidylinositol substrates, leading to formation of two phosphatidylinositol 3-phosphates: PI(3,4)P2 or I(3,4,5)P3

C. PI-3 kinase pathway can trigger cell division and prevent apoptosis, thus ensuring cell survival by the activation of PKB.

D. Activated PKB phosphorylates FOXO3a, which induces the expression of several antiapoptotic genes.

Which of the following combination is correct?

#Question id: 4809

#Unit 8. Inheritance Biology

The upper most following figure above shows the locations of four genes on the genetic map of an organism; the lower figure shows the locations of the same four genes on a physical map derived from the nucleotide sequence of the DNA of that organism. The maps are not identical because

#Question id: 4810

#Unit 8. Inheritance Biology

In a haploid organism, the C and D loci are 8 m.u. apart. From a cross C d X c D, which of the following proportion following progeny classes: (a) C D; (b) c d; (c) C d

#Question id: 4811

#Unit 8. Inheritance Biology

Three incompletely link gene as a B-A-C order. A cross allowed between AAbbcc X aaBBCC produce f1 progeny allowed test cross. Which of the following offspring is a result of double cross over?

#Question id: 4812

#Unit 8. Inheritance Biology

Two character X and Y ,both follow law of dominance due to 3:1 F2 phenotypic ratio monohybrid cross separately If carry out dihybrid selfing cross for heterozygous genotype for both character does not follow law of independence assortment in normal environmental condition due to?

#Question id: 4813

#Unit 8. Inheritance Biology

You perform the three different two-factor crosses (Cross 1: XY and xy, Cross 2: YZ and yz, and Cross 3: XZ and xz). Assume all crosses are between diploid flies homozygous for the alleles of these genes. You observe 7% recombinants in the first cross, 20% recombinants in the second cross, and 13% recombinants in the third cross. if cross between XyZ and xYz leads to which of the followining recombinant with double cross over .

#Question id: 4814

#Unit 8. Inheritance Biology

The frequency of recombinant gametes is half the frequency of crossing over between genes present on same chromosome is due to