Practice Questions

TLS Online TPP Program

#Question id: 1260

Which of the following statement regarding RTK/Ras pathway is incorrect?

#Unit 4. Cell Communication and Cell Signaling

Receptor activation leads to re-localization of Sos from the cytosol to the membrane, which brings Sos close to its substrate, Ras∙GDP, which is already bound to the plasma membrane by means of a covalently attached lipid.
Binding of Sos to Ras∙GDP leads to conformational changes in the switch I and switch II segments of Ras, thereby opening the binding pocket for GDP so it can diffuse out.
The SH2 domains in GRB2 selectively bind to proline-rich sequences in Sos; different SH3 domains in other proteins bind to proline-rich sequences distinct from those in Sos.
Ras is activated by the exchange of GDP for GTP. Active Ras∙GTP binds to the N-terminal regulatory domain of Raf, a serine/threonine kinase, thereby activating its kinase activity.

More Questions

TLS Online TPP Program

#Question id: 10444

#Unit 6. System Physiology – Plant

Which protein is involved in the crosstock signalling with the phytochrome and initiates photomorphogenesis?

TLS Online TPP Program

#Question id: 10445

#Unit 6. System Physiology – Plant

Arabidopsis plants overexpressing a type of region that shows the phenotypic similarity with the cop mutants, which resemble light-grown seedlings when grown in darkness. The region is____

TLS Online TPP Program

#Question id: 10446

#Unit 6. System Physiology – Plant

CIB1 (Cry-Interacting basics helix loop helix) initiates____

TLS Online TPP Program

#Question id: 10447

#Unit 6. System Physiology – Plant

phot2 mediates phototropism in response to

TLS Online TPP Program

#Question id: 10448

#Unit 6. System Physiology – Plant

Fusion proteins of phytochrome and phototropins known as neochrome, the structure neochrome contains