#Question id: 7127
#Unit 5. Developmental Biology
The immunoglobulin genes are expressed in B-cells, and the b-globin gene is expressed in red blood cells. What manipulations might be carried out to get the b-globin gene to be expressed in B-cells?
#Question id: 7128
#Unit 5. Developmental Biology
Imagine that in an attempt to get the â-globin gene to be expressed in B-cells, the transcription factors (GATA-1 and GATA-2) known to control the â-globin gene in erythrocytes were introduced into B-cells, yet the â-globin gene was not expressed. What is a likely explanation for this result?
#Question id: 7129
#Unit 5. Developmental Biology
What is the developmental pathway by which the hematopoietic stem cell gives rise to a macrophage?
#Question id: 7130
#Unit 5. Developmental Biology
Hematopoietic stem cells can be isolated and grown in culture; if one wished to control their differentiation into either neutrophils or macrophages, what colony stimulating factors could be used?
#Question id: 7131
#Unit 5. Developmental Biology
What is globin gene switching?
#Question id: 7132
#Unit 5. Developmental Biology
What happens if you introduce the gene myoD into fibroblast cells growing in culture?