Following statements are regarding to the formins which involve in filament assembly.

A. All formin family members have two adjacent domains in common, the so called FH1 and FH2 domains (formin-homology domains 1 and 2).

B. Two FH2 domains from two individual formin monomers associate to form a doughnut-shaped complex can form a dimer and nucleate filament assembly.

C. The FH1 domain of formin is rich in proline residues, which serve as sites for the binding of several profilin molecules.

D. The FH2 domain behaves as a landing site for profilin–ATP–G-actin to increase the local concentration of these complexes.

E. Formins are activated by membrane bound Rho-GTP, a Ras-related small GTPase.

Which of the following combination is correct?

#Question id: 27946

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 27947

#Unit 1. Molecules and their Interaction Relevant to Biology

For each molecule of glucose degraded to pyruvate, two molecules of ATP are generated from ADP and Pi, and two molecules of NADH are produced by the reduction of NAD+. The hydrogen acceptor in this reaction is NAD+  this NAD+ bound to a

#Question id: 27948

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 27949

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following reaction is catalyzed by enzyme phosphohexose isomerase (phosphoglucose isomerase)

#Question id: 27950

#Unit 1. Molecules and their Interaction Relevant to Biology

Some of the properties of Hexokinases I, II, III & IV is given

a. Hexokinases I, II, and III shows hyperbolic curve of glucose binding while Hexokinase IV shows sigmoidal curve 

b. Accumulation of glucose 6-phosphate inhibits hexokinases I–III by feedback mechanism 

c. Accumulation of glucose 6-phosphate allosterically inhibits hexokinases I–III.

d. The allosteric effector of Hexokinase IV is fructose 6-phosphate.

Which of the following is incorrect  

#Question id: 27951

#Unit 1. Molecules and their Interaction Relevant to Biology