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TLS Online TPP Program

#Question id: 14766

Which of the following statements does not belongs to the regulatory mechanism of the Arp2/3 complex by WASp and PI(4,5)P2?

#Unit 2. Cellular Organization
  1. The NPF WASp is inactive due to an intramolecular interaction that masks the WCA domain. 
  2. NPF WASp is activated by a coincidence detection mechanism, it must bind both the regulatory phospholipid PI(4,5)P2 though its basic domain (B) and the membrane-bound active small G protein Cdc42-GTP through its Rho-binding domain. 
  3. When activated by the Cdc42-GTP, the intramolecular interaction in WASp is relieved, allowing the W domain to bind actin and the acidic A domain to activate the Arp2/3 complex.
  4. The Arp2/3 branch makes a characteristic 70° angle between the old and new filaments.
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TLS Online TPP Program

#Question id: 28269

#Unit 5. Developmental Biology

Sperm-specific calcium channels are encoded by which gene? 
TLS Online TPP Program

#Question id: 28270

#Unit 5. Developmental Biology

 Increase in cGMP and Ca2+ stimulates flagellar movement in the sperm by activating__ 
a) mitochondrial GTP-generating apparatus 
b) mitochondrial ATP-generating apparatus
c) Na+/K+ ATPase
d) dynein ATPase
TLS Online TPP Program

#Question id: 28271

#Unit 5. Developmental Biology

Kartagener triad syndrome is caused due to the___ 
TLS Online TPP Program

#Question id: 28272

#Unit 5. Developmental Biology

sulfate-containing polysaccharides in the egg jelly is responsible for___ 
TLS Online TPP Program

#Question id: 28273

#Unit 5. Developmental Biology

In sea urchins, the acrosome reaction is initiated by_____
TLS Online TPP Program

#Question id: 28274

#Unit 5. Developmental Biology

In case of sea urchin (Strongylocentrotus purpuratus), the acrosome reaction is initiated by_____