Secondary immune response to a hapten depends on the: 

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#Question id: 17809

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. What is the probability that a child will be albino if: Both parents are members of Generation 2, and one parent is albino and the other is non-albino.

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#Question id: 17994

#Unit 8. Inheritance Biology

Consider a heritable autosomal disease with an incidence in the population of 1 per thousand. On average, individuals with the disease have 80% as many children as the population average. In answering the various parts of this question, assume that mating is random. What mutation rate would be required to maintain the observed incidence of the disease in the population if the disease is dominant?

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#Question id: 17995

#Unit 8. Inheritance Biology

Consider a heritable autosomal disease with an incidence in the population of 1 per thousand. On average, individuals with the disease have 80% as many children as the population average. In answering the various parts of this question, assume that mating is random. What mutation rate would be required to maintain the observed incidence of the disease in the population if the disease is recessive?

TLS Online TPP Program

#Question id: 17996

#Unit 8. Inheritance Biology

Consider a heritable autosomal disease with an incidence in the population of 1 per thousand. On average, individuals with the disease have 80% as many children as the population average. In answering the various parts of this question, assume that mating is random. Now assume that the mutation rate is zero, that the disease is recessive, and that the disease allele is maintained in the population by heterozygote advantage. Calculate the heterozygote advantage,

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#Question id: 18081

#Unit 8. Inheritance Biology

The interaction of selection and inbreeding in determining the incidence of autosomal recessive diseases. Consider a gene in which recessive mutations occur at a rate of 10^-5. Assume a selective disadvantage S of 0.4 in homozygotes for the recessive allele. What is the frequency of the recessive allele (q). And calculate the incidence of the disease. Assume random mating.

TLS Online TPP Program

#Question id: 18082

#Unit 8. Inheritance Biology

The interaction of selection and inbreeding in determining the incidence of autosomal recessive diseases. Consider a gene in which recessive mutations occur at a rate of 10^-5. Assume a selective disadvantage S of 0.4 in homozygotes for the recessive allele. Now assume that, for thousands of generations, 10% of all children have been products of first-cousin matings (the remaining 90% being products of random matings). Calculate the steady-state value of q. Also calculate the incidence of the disease at steady state.