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TLS Online TPP Program

#Question id: 14812

Size and foreignness are not, by themselves, sufficient to make a molecule immunogenic; other properties are needed as well. Which one is not correct immunogenic properties?

#Unit 4. Cell Communication and Cell Signaling
  1. synthetic homopolymers  (polymers composed of a single amino acid or sugar) tend to lack immunogenicity regardless of their size.
  2. that copolymers composed of different amino acids or sugars are usually more immunogenic than homopolymers of their constituents.
  3. greater the phylogenetic distance between two species causes lower immunogenic 
  4. bovine serum albumin (BSA) is not immunogenic when injected into a cow but is strongly immunogenic when injected into a rabbit.
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TLS Online TPP Program

#Question id: 12995

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following constraints affect the stability α-helix, 
a) the intrinsic propensity of an amino acid residue to form an α-helix.
b) the interactions between R groups.
c) the bulkiness of adjacent R groups.
d) the occurrence of Pro and Gly residues.
TLS Online TPP Program

#Question id: 12996

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is incorrect regarding to α-helix
a) In the α helix, the first four NH groups and last four CO groups will normally lack backbone  hydrogen bonds.
b) the length of an amino acid in α-helix reduced almost 3 times than linear structure.
c) the frequent occurrence of Pro and Gly residues favour α-helix formation.
d) dihedral (ϕ and ψ) angle should be close to -57 and -47.
TLS Online TPP Program

#Question id: 12997

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the given reason is correct to minimize the repulsion in an α-helix
a) positively charged amino acids are often found near the amino terminus of the helical segment
b) negatively charged amino acids are often found near the amino terminus of the helical segment
c) positively charged amino acids are often found near the C-terminus of the helical segment.
d) negatively charged amino acids are often found near the C-terminus of the helical segment.
TLS Online TPP Program

#Question id: 12998

#Unit 1. Molecules and their Interaction Relevant to Biology

Match with appropriate bonding pattern
TLS Online TPP Program

#Question id: 12999

#Unit 1. Molecules and their Interaction Relevant to Biology

Proline and glycine both disturb the symmetry of α-helix which of the following are true regarding to these two amino acids
a) proline changes the orientation of hetropolymeric α-helix hence proline can be placed only as 1st amino acid residue near to C-terminus 
b) proline changes the orientation of polymeric α-helix hence proline can be placed only as 1st amino acid residue near to N-terminus
c) glycine disrupts the heteropolymeric α-helix by changing the helicity.
d) homopolymer of proline and glycine can form stable helix. 
TLS Online TPP Program

#Question id: 13000

#Unit 1. Molecules and their Interaction Relevant to Biology

Identify the correct statement regarding the structure