Practice Questions

TLS Online TPP Program

#Question id: 14829

A new drug is developed that inhibits formation of the flagellar filament by impairing production of the protein flagellin. Is this going to be a good drug?

#Unit 2. Cellular Organization

Potentially-it would definitely only impair bacteria, but wouldn't matter for the ones that don't use a flagellum to move around.
Potentially-if it could be shown that it also didn't impair the production of the eukaryotic flagellum.
No-our eukaryotic cells depend on flagella to move around in our body, and this would impair that function.
No-bacterial flagella are produced using microtubules, not the protein flagellin. This drug would be useless in eliminating bacteria.

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TLS Online TPP Program

#Question id: 26446

#Unit 3. Fundamental Processes

Which of the following is a universal marker for double strand breaks

TLS Online TPP Program

#Question id: 26447

#Unit 3. Fundamental Processes

Which polymerases are template-dependent, they incorporate nucleotides in a manner that is independent of base pairing

TLS Online TPP Program

#Question id: 26448

#Unit 3. Fundamental Processes

Choose the correct statement regarding DNA photolyase

a.MTHF polyglu absorb blue light photon of 300-500 nm

b.And the MTHF polyglu radicalize FADH cofactor

c.And this FADH cofactor donate single electron to CBD

d.And this FADH cofactor donate many electron to CBD

TLS Online TPP Program

#Question id: 26449

#Unit 3. Fundamental Processes

Ability of core and holoenzyme to transcribe DNAs differs, so choose which of the following is correct

a.With subunit, the holoenzyme worked equally well on both intact as well as nicked types of DNA

b.With subunit, the holoenzyme worked unequally on both intact as well as nicked types of DNA

c.Core subunit α2ββσ can not perform polymerization on to the intact DNA while perform some of the activity on to the nicked DNA

d.Core subunit α2ββσ can not perform polymerization on to the intact DNA AS WELL AS to the nicked DNA

TLS Online TPP Program

#Question id: 26450

#Unit 3. Fundamental Processes

Which of the following statements is true regarding bacterial RNA polymerase

a. Core enzyme can efficiently transcribe both intact and nicked DNA

b. Sigma destabilizes nonspecifically bound core

c. Holoenzyme bind tightly to DNA

d. Higher disassociation rate at lower temperature

e. Most of the cellular sigma are house keeping gene

TLS Online TPP Program

#Question id: 26451

#Unit 3. Fundamental Processes

Which of the following characteristics of sigma affect non specific binding of the core