TLS Online TPP Program

#Question id: 14969


 A new drug is developed that targets and binds to the lipid A portion of LPS from Gram negative bacterial cells. This drug shows a high degree of activity and binding in a test tube setting against purified lipid A. Based on this information,

#Unit 2. Cellular Organization
  1. We should fast track this drug and get it out to physicians immediately to help prevent toxic/septic shock in humans.
  2. We should do some animal testing with whole Gram-negative cells and the drug before we jump to any conclusions.
  3. We should next proceed by moving to testing in a test tube using whole Gram-negative cells to see if it binds with the same strength.
  4. We should abandon the drug entirely binding to lipid A won't kill the bacteria, so the drug is useless to develop further