TLS Online TPP Program

#Question id: 14969


 A new drug is developed that targets and binds to the lipid A portion of LPS from Gram negative bacterial cells. This drug shows a high degree of activity and binding in a test tube setting against purified lipid A. Based on this information,

#Unit 2. Cellular Organization
  1. We should fast track this drug and get it out to physicians immediately to help prevent toxic/septic shock in humans.
  2. We should do some animal testing with whole Gram-negative cells and the drug before we jump to any conclusions.
  3. We should next proceed by moving to testing in a test tube using whole Gram-negative cells to see if it binds with the same strength.
  4. We should abandon the drug entirely binding to lipid A won't kill the bacteria, so the drug is useless to develop further
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TLS Online TPP Program

#Question id: 8700

#Unit 9. Diversity of Life Forms

Use the following figure and description to answer the question.

Humans, chimpanzees, gorillas, and orangutans are members of a clade called the great apes, which shared a common ancestor about 15 million years ago. Gibbons and siamangs comprise a clade called the lesser apes. Tree-branch lengths indicate elapsed time. Assuming chimps and gorillas are humans' closest relatives, removing humans from the great ape clade and placing them in a different clade has the effect of making the phylogenetic tree of the great apes ________.

TLS Online TPP Program

#Question id: 8701

#Unit 9. Diversity of Life Forms

The question refers to the following table, which compares the percent sequence homology of four different parts (two introns and two exons) of a gene that is found in five different eukaryotic species. Each part is numbered to indicate its distance from the promoter (for example, Intron I is the one closest to the promoter). The data reported for species A were obtained by comparing DNA from one member of species A to another member of species A.


Based on the tabular data, and assuming that time advances vertically, which phylogenetic tree is the most likely depiction of the evolutionary relationships among these five species?

TLS Online TPP Program

#Question id: 8702

#Unit 9. Diversity of Life Forms

The question refers to the following table, which compares the percent sequence homology of four different parts (two introns and two exons) of a gene that is found in five different eukaryotic species. Each part is numbered to indicate its distance from the promoter (for example, Intron I is the one closest to the promoter). The data reported for species A were obtained by comparing DNA from one member of species A to another member of species A.

Regarding these sequence homology data, the principle of maximum parsimony would be applicable in ________.

TLS Online TPP Program

#Question id: 8703

#Unit 9. Diversity of Life Forms

In a comparison of birds and mammals, having four limbs is ________.

TLS Online TPP Program

#Question id: 8704

#Unit 9. Diversity of Life Forms

To apply the principle of maximum parsimony to construction of a phylogenetic tree, ________.

TLS Online TPP Program

#Question id: 8705

#Unit 9. Diversity of Life Forms

If you were using cladistics to build a phylogenetic tree of cats, which of the following would be the best outgroup?