TLS Online TPP Program

#Question id: 15003


Laurie met her husband Jim at a support group for families dealing with PKU (phenylketonurea), a recessive genetic disorder. Laurie and Jim both have one sister who is affected with PKU and no other family history of the disorder. They come to you as a genetic counselor to ask what their risk is of having an affected child. What do you tell them?

#Unit 8. Inheritance Biology
  1. They must both be heterozygotes so their risk of having an affected child is ΒΌ.
  2. They must both be heterozygotes so their should tested to see if they carry the disease allele or not
  3. Since neither one of them is affected, they are not at risk of having an affected child.
  4. You can't give them any firm answers because you don't know their genotypes.
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TLS Online TPP Program

#Question id: 31360

#Unit 3. Fundamental Processes

Histone deacetylase belongs to the class of 

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#Question id: 31402

#Unit 3. Fundamental Processes


TLS Online TPP Program

#Question id: 34086

#Unit 3. Fundamental Processes

Replicators/replicons can be identified using a 

TLS Online TPP Program

#Question id: 34087

#Unit 3. Fundamental Processes

A DNA containing which an origin of replication undergoing to initiation of replication and further, is digested with restriction endonuclease. Which shape of DNA segment can be found after digestion followed electrophoresis.
A. Y Shape B. Bubble shape C. bubble-to-Y-arc D. Circular

TLS Online TPP Program

#Question id: 34088

#Unit 3. Fundamental Processes

How can the 2D gels identify the DNA intermediates associated with a replication origin? Choose combination of correct statements

A. Y-shaped molecule that has three equal length arms will migrate the most slowly of all such molecules derived from a particular DNA fragment
B. A Y-shaped molecule with two very short replicated arms and a large replicated region will migrate very similarly to the unreplicated version of the same DNA fragment. 
C. Y-shaped molecule that results from the almost completely replicated fragment is similar in shape to a linear molecule two times the size of the unreplicated fragment.

TLS Online TPP Program

#Question id: 34089

#Unit 3. Fundamental Processes

A. Replication Initiation require full methylation of the Dam target sites in the origin
B. Replication Initiation inhibited by hemimethylation of Dam target sites 
C. Replication Initiation inhibited by nonmethylation of Dam target sites 
D. An origin of nonmethylated DNA can function effectively

Choose true and false