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TLS Online TPP Program

#Question id: 15003

Laurie met her husband Jim at a support group for families dealing with PKU (phenylketonurea), a recessive genetic disorder. Laurie and Jim both have one sister who is affected with PKU and no other family history of the disorder. They come to you as a genetic counselor to ask what their risk is of having an affected child. What do you tell them?

#Unit 8. Inheritance Biology
  1. They must both be heterozygotes so their risk of having an affected child is ¼.
  2. They must both be heterozygotes so their should tested to see if they carry the disease allele or not
  3. Since neither one of them is affected, they are not at risk of having an affected child.
  4. You can't give them any firm answers because you don't know their genotypes.
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TLS Online TPP Program

#Question id: 12699

#Unit 7. System Physiology – Animal

The following test results were obtained: urine flow rate = 2.0 ml/min; urine inulin concentration = 60 mg/ml; plasma inulin concentration = 2 mg/ml; urine potassium concentration = 20 μmol/ml; plasma potassium concentration = 4.0 μmol/ml; urine osmolarity = 150 mOsm/L; and plasma osmolarity = 300 mOsm/L. What is the free water clearance rate?
TLS Online TPP Program

#Question id: 12700

#Unit 7. System Physiology – Animal

A young man is found comatose, having taking an unknown number of sleeping pills an unknown time before. An arterial blood sample yields the following values: pH = 7.02, HCO3− = 14 mEq/L, and PCO2 = 68 mm Hg. This patient’s acid–base status is most accurately described as
TLS Online TPP Program

#Question id: 12701

#Unit 7. System Physiology – Animal

In chronic respiratory acidosis with partial renal compensation, you would expect to find the following changes, compared to normal:___ urinary excretion of NH4+; ______ plasma HCO3− concentration; and _____ urine pH.
TLS Online TPP Program

#Question id: 12949

#Unit 7. System Physiology – Animal

At which renal tubular sites would the concentration of creatinine be expected to be highest in a normally hydrated person?
TLS Online TPP Program

#Question id: 12950

#Unit 7. System Physiology – Animal

Increases in both renal blood flow and GFR are caused by which of the following?
TLS Online TPP Program

#Question id: 12951

#Unit 7. System Physiology – Animal

If the cortical collecting tubule tubular fluid inulin concentration is 40 mg/100 ml and plasma concentration of inulin is 2.0 mg/100 ml, what is the approximate percentage of the filtered water that remains in the tubule at that point?