The recessive mutant allele that causes cystic fibrosis is much more frequent in Caucasians population than in other world populations. Some scientists believe heterozygotes must have had a survival advantage during plagues such as cholera that occasionally swept through this population. What concept does this illustrate?

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#Question id: 33904

#Unit 2. Cellular Organization

A. The bacterial nucleoid is 80% DNA by mass.

B. Bacteria have similar morphological features as of eukaryotic chromosomes, 

C. Bacterial genomes are organized into definite substructures within the cell. 

D. Bacterial Protein HU is a dimer that condenses DNA, possibly wrapping it into a beadlike structure.

Find true and false

TLS Online TPP Program

#Question id: 33905

#Unit 2. Cellular Organization

E. coli DNA in vivo corresponds to an average density of 1 negative superhelical turn/200 bp it means it has 

TLS Online TPP Program

#Question id: 33906

#Unit 2. Cellular Organization

Which is correct combination of statements

A. Bacterial genome has independent sets of domains and each domain consists of a loop of DNA.

B. Presence of domain in genome can be analyzed by EtBR intercalation and DNase treatment 

C. Early data suggested that each domain consists of 10kb-40 kb of DNA

TLS Online TPP Program

#Question id: 33907

#Unit 2. Cellular Organization

A circular DNA molecule with 580,070 bp. Calculate the molecular weight and contour length (when relaxed) of this molecule. What is Lko for the Mycoplasma chromosome? If σ=-  0.06, what is Lk?

TLS Online TPP Program

#Question id: 33908

#Unit 2. Cellular Organization

How is the linking number altered if one DNA strand is broken

TLS Online TPP Program

#Question id: 33909

#Unit 2. Cellular Organization

What is the Lk of a 5,000 bp circular duplex DNA molecule with a nick in one strand?