TLS Online TPP Program

#Question id: 15287


Following are postulates of mechanism of differentiation. Which of the following is incorrect?

#Unit 5. Developmental Biology
  1. Every somatic cell nucleus of an organism contains the complete genome established in the fertilized egg, it means the DNAs of all differentiated cells are identical.
  2. The unused genes in differentiated cells are neither destroyed nor mutated; they retain the potential for being expressed.
  3. Only used genes have the potential for being expressed while unused genes  are either destroyed or mutated.
  4. Only a small percentage of the genome is expressed in each cell, and a portion of the RNA synthesized in each cell is specific for that cell type
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TLS Online TPP Program

#Question id: 5801

#Unit 8. Inheritance Biology

Which of the following point mutations would be most likely to affect protein function?

TLS Online TPP Program

#Question id: 5802

#Unit 8. Inheritance Biology

A wild type allele:

TLS Online TPP Program

#Question id: 5803

#Unit 8. Inheritance Biology

The mutation which causes sickle cell anemia in humans:

TLS Online TPP Program

#Question id: 5804

#Unit 8. Inheritance Biology

The gene that is mutated in cases of cystic fibrosis encodes an ion transporter protein normally expressed in the respiratory and digestive tracts along with other locations. Individuals homozygous for the most common mutation in this gene (ΔF508) died at very early ages prior to the advent of advanced medical intervention. Despite this, the mutation exists at relatively high frequency in populations of European descent. One potential explanation is that heterozygotes for such mutations may be relatively immune to the lethal effects of diseases such as typhoid fever. Which statement below is most accurate?

TLS Online TPP Program

#Question id: 5805

#Unit 8. Inheritance Biology

In Himalayan rabbits, the ears, feet, and muzzle are pigmented while the rest of the body is white. This is because they express an enzyme variant that is ineffective at body temperature but functions at the lower temperatures experienced by cells of the extremities. This is an example of:

TLS Online TPP Program

#Question id: 5806

#Unit 8. Inheritance Biology

Which of these is NOT a mechanism by which a chromosome rearrangement could affect gene function?