The chemical benzo(a)pyrene, found in cigarette smoke as well as in coal tar, undergoes metabolic activation in the lungs to form a potent mutagen that mainly, causes conversion of guanine (G) to thymine (T) bases, a transversion mutation, When applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including inactivating mutations of the p53 gene, at codon number______

TLS Online TPP Program

#Question id: 33519

#Unit 2. Cellular Organization

Assertion: Some genes are present in more than one copy or are related to one another. 

Reason: Number of different types of genes is less than the total number of genes.

TLS Online TPP Program

#Question id: 33520

#Unit 2. Cellular Organization

What can be correctly inferred from the figure shown here.

A. Many genes are duplicated

B. Number of different gene families is larger than the total number of genes

C. A gene family arises by repeated duplication of an ancestral gene followed by accumulation of changes in sequence among the copies

TLS Online TPP Program

#Question id: 33521

#Unit 2. Cellular Organization

Operationally, we usually consider that two genes are orthologs if 

TLS Online TPP Program

#Question id: 33522

#Unit 2. Cellular Organization

Alignment of two entire genome sequences and comparison of the locations of orthologs is done by

A. BLAST

B. MUMmer

C. InterPreTS

D. ProtoNet

TLS Online TPP Program

#Question id: 33523

#Unit 2. Cellular Organization

The fruit fly genome can be divided into genes as shown in the figure. Which statement is incorrect according to the figure given?

TLS Online TPP Program

#Question id: 33524

#Unit 2. Cellular Organization

A. Only 1% of the human genome consists of exons.

B. The genes (exons plus introns) comprise 25% of the genome.

C. 60% of human genes are alternatively spliced.

D. Up to 80% of the alternative splices change protein sequence, so the human proteome has 50,000 to 60,000 members.

Find true and false statements