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TLS Online TPP Program

#Question id: 15363

Epithelial-to-mesenchymal transition (EMT) is thought to play a crucial role during the process of metastasis in some cancers, Snail and Twist are the two transcription factors, function as EXCEPT

#Unit 4. Cell Communication and Cell Signaling
  1. reduce the expression of genes involved in cell migration
  2. trigger down-regulation of cell-adhesion factors
  3. increase the production of proteases
  4. Snail-G9a-Dnmts complex binds to the fructose-1,6-biphosphatase(FBP1) promoter and silences FBP1 expression in basal-like breast cancer
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TLS Online TPP Program

#Question id: 1949

#Unit 4. Cell Communication and Cell Signaling

IgG in patients with rheumatoid arthritis has abnormal:
TLS Online TPP Program

#Question id: 32330

#Unit 1. Molecules and their Interaction Relevant to Biology

The parietal cells of the stomach lining contain membrane “pumps” that transport hydrogen ions from the cytosol (pH 7.0) into the stomach, contributing to the acidity of gastric juice (pH 1.0). Calculate the free energy required to transport 1 mol of hydrogen ions through these pumps. (Hint: see Chapter 11.) Assume a temperature of 37 °C.
TLS Online TPP Program

#Question id: 7097

#Unit 5. Developmental Biology

What property of the mammalian embryo permits the production of chimeric mice?
TLS Online TPP Program

#Question id: 7087

#Unit 5. Developmental Biology

In case of xenopus laevis which cells make up the Niuewkoop center?
TLS Online TPP Program

#Question id: 5659

#Unit 5. Developmental Biology

 Following are the statements related to mammalian chaemotaxis .
A. During chaemotaxis, the oocyte and its accompanying cumulus cells secrete molecules that attract only uncapacitated sperm toward the egg during the last stages of sperm migration.
B. These chaemotactic compound are hormone progesterone, which is made by the cumulus cells.
C. Progesterone has been shown to bind to a receptor that activates Ca2+ channels in the cell membrane of the sperm tail, leading to sperm hyperactivity and provides directional cue.
D. Cumulus cells also secrete a substance, CRISP1, that attracts sperm and hyperactivates them through CatSper channels similar as in sea urchins.
Which of  the following statement is incorrect?