For pro-proliferation signaling pathways to cause uncontrolled proliferation, as is seen in cancer, this p53 up-regulation must not occur, It is therefore not surprising that p53 is inactive in most human tumors through loss of p53 function itself, down-regulation of positive regulators (PR) of p53 or up-regulation of negative regulators (NR) of p53, these regulators are accordingly

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#Question id: 31370

#Unit 5. Developmental Biology

Which would lead to a ventralized embryo in drosophila? 

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#Question id: 31372

#Unit 5. Developmental Biology

Following statements are regarding lens induction in xenopus. choose incorrect statement?

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#Question id: 31374

#Unit 5. Developmental Biology

For induction of limb bud growth Fgf8-secreting beads can substitute for the: 

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#Question id: 31378

#Unit 5. Developmental Biology

The following experimental manipulations were carried out with Xenopus embryo.

Manipulation X: Exposure to UV radiation leading to the failure of cortical rotation.

Manipulation Y: Gastrulae treated with lithium chloride.

The following statements were made with respect to the above manipulations. Which one of the following represents correct statement?

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#Question id: 31379

#Unit 5. Developmental Biology

The cadherin catenin complex is extremely important during compaction from a morula to the blastula. Transition of early embryonic cells into a blastula differed depending on the presence or absence of calcium ions. In addition, an investigator blocked the expression of β-catenin using vivo morpholinos to detect its effect simultaneously on compaction. Which one of the following conditions will lead to the most successful transition of the morula into the blastula?

TLS Online TPP Program

#Question id: 31384

#Unit 5. Developmental Biology

In drosophila, the third thoracic segment is transformed into another second thoracic segment due to: