Following statements are regarding to gap junctions.

i. Vertebrate gap junctions are composed of connexins, a family of structurally related transmembrane proteins with molecular weights between 26,000 and 60,000.

ii. Each vertebrate hexagonal particle consists of six noncovalently associated connexin molecules. Each individual connexin molecule has two membrane-spanning α helices with a topology similar to that of claudin.

iii. The permeability of gap junctions is regulated by posttranslational modification of connexins (e.g., phosphorylation) and is sensitive to changes in environmental conditions

such as intracellular pH and Ca2+ concentration, membrane potential, and the intercellular potential between adjacent interconnected cells (“voltage gating”).

iv. The assembly of connexins, their trafficking within cells, and the formation of functional gap junctions apparently depend on N-cadherin and its associated adapter proteins as well as desmosomal proteins.

Which of the following statements are correct?

TLS Online TPP Program

#Question id: 15530

#Unit 4. Cell Communication and Cell Signaling

The activity of already differentiated effector and memory T cells is maintained by a receptor which are generally expressed on the memory and effector T cells. 

TLS Online TPP Program

#Question id: 15542

#Unit 8. Inheritance Biology

How would you expect a mutation in a gene encoding a tail fiber protein would affect the plaque phenotype of T4?

TLS Online TPP Program

#Question id: 15543

#Unit 8. Inheritance Biology

In Benzer's intragenic mapping experiments, what event was required to allow production of infectious phage from rII mutants?

TLS Online TPP Program

#Question id: 15559

#Unit 12. Applied Biology

The majority of the antibiotics have been isolated from 

TLS Online TPP Program

#Question id: 15560

#Unit 12. Applied Biology

Nearly all of the genetic improvements to industrially important antibiotic-producing strains have been achieved by the use of 

TLS Online TPP Program

#Question id: 15561

#Unit 12. Applied Biology

Which mechanism is helpful in secondary metabolite production

1. ppGpp secretion

2. Autoinducer

3. Nutrient limitation

4. Senescence genes

Which combination is incorrect  from the following.