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TLS Online TPP Program

#Question id: 15443

The caspases have which amino acid residues in their catalytic site and what is the cleavage site of these effector proteases;

#Unit 4. Cell Communication and Cell Signaling
  1. Aspartate residue in the catalytic site and cleave proteins at sites just N-terminal to cysteine residues.
  2. Cysteine residue in the catalytic site and cleave proteins at sites just C-terminal to aspartate residues. 
  3. Glutamine residue in the catalytic site and cleave proteins at sites just C-terminal to cysteine residues.
  4. Isoleucine residue in the catalytic site and cleave proteins at sites just N-terminal to aspartate residues.
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TLS Online TPP Program

#Question id: 2437

#Unit 2. Cellular Organization

Membrane extension involves

a. bending actin filaments.                   

b. myosin II.

c. the Arp2/3 nucleation of new filaments.

d. actin depolymerization.     

e. actin polymerization.
TLS Online TPP Program

#Question id: 2438

#Unit 2. Cellular Organization

Rac, a GTPase superfamily protein,

a. is related to Ras.                             

b. may be activated by growth factors.

c. stimulates lamellipodia formation. 

d. stimulates filopodia formation.

e. stimulates stress fiber assembly.
TLS Online TPP Program

#Question id: 2439

#Unit 2. Cellular Organization

α- and β-tubulin

a. are highly conserved.                                 

b. bind GTP.

c. hydrolyze GTP to GDP.                 

d. are found in all eukaryotes.

e. are related to the bacterial protein FtsZ.
TLS Online TPP Program

#Question id: 2440

#Unit 2. Cellular Organization

Microtubule assembly in vitro requires

a. ATP.                                                           

b. a threshold (critical) concentration of tubulin.

c. warming the solution to 37°C.                   

d. microtubule-associated proteins.         

e. GTP.
TLS Online TPP Program

#Question id: 2441

#Unit 2. Cellular Organization

Which of the following statement(s) is (are) true of microtubule assembly?

a. GDP-tubulin normally assembles into microtubules.

b. Microtubule (-) ends grow faster than microtubule (+) ends.

c. Tubulin subunits assemble to form a protofilament.

d. Microtubules consist of multiple protofilaments.

e. Microtubules with a GTP cap will shorten.
TLS Online TPP Program

#Question id: 2442

#Unit 2. Cellular Organization

The drug colchicine acts to

a. promote microtubule assembly.     

b. inhibit microtubule assembly.

c. sever microtubules.                        

d. block cell division.

e. cap microtubule ends.