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TLS Online TPP Program

#Question id: 1389

 Why has C. elegans proven to be a useful model for understanding apoptosis?

#Unit 4. Cell Communication and Cell Signaling

  1. C. elegans does not naturally use apoptosis, but can be induced to do so in the laboratory.

  2. C. elegans undergoes a fixed and easy-to-visualize number of apoptotic events during its normal development.

  3. C. elegans has large cells wherein apoptosis is easily observed without the aid of a microscope.

  4. As C. elegans ages, its cells die progressively until the whole organism is dead.

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TLS Online TPP Program

#Question id: 19112

#Unit 8. Inheritance Biology

the frequency of PKU among newborns is approximately 1/10,000 (when the parents are unrelated). What is the risk of a child with PKU if the parents are second cousins?
TLS Online TPP Program

#Question id: 19113

#Unit 8. Inheritance Biology

P, Q, and R are three different inbred, true-breeding strains of mice. A hybrid between P and Q is mated to R, and a hybrid between Q and R is mated to P. A male from the first mating is mated to a female from the second mating. What is the inbreeding coefficient of their progeny?
TLS Online TPP Program

#Question id: 19114

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:
                                       
Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR42 in Family 1.
TLS Online TPP Program

#Question id: 19115

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:
                
Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR43 in Family 1.
TLS Online TPP Program

#Question id: 19116

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:
                             
Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR42 in Family 2.
TLS Online TPP Program

#Question id: 19117

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:
 
Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR43 in Family 2.