TLS Online TPP Program

#Question id: 15657


You are studying a new strain of E. coli that can utilize the disaccharide melibiose very efficiently. You find that utilization depends on the enzyme melibiase, which is encoded by the gene Mel1. Mel1 is not expressed unless melibiose is present in the growth medium.
You next construct a MelA– MelB– double mutant, which gives the following behavior:
 
Which of your two models is consistent with this new data?
a) the MelA- MelB- double mutant is identical to the MelB- mutant
b) MelA- is epistatic to MelB-
c) MelB- is epistatic to MelA-
d) the MelA- MelB- double mutant is identical to the MelA- mutant
Which of the following is the correct prediction about the double mutants?

#Unit 13. Methods in Biology
  1. A and C
  2. B and D
  3.  C and D
  4. A and B