A mouse heterozygous at the Igf-2 locus is dwarf and has 50% dwarf progeny when mated to a homozygous Igf-2m animal. Which statement about this animal is FALSE?

#Question id: 1394

#Unit 4. Cell Communication and Cell Signaling

Apoptosis involves all but which of the following?

#Question id: 1395

#Unit 4. Cell Communication and Cell Signaling

Which of the following mutations would promote malignancy in cells whose proliferation is inhibited by TGFβ?

a. overexpression of Smad2               

b. loss of Smad 4

c. overexpression of TGFβ receptor I

d. loss of TGFβ receptor II

#Question id: 1396

#Unit 4. Cell Communication and Cell Signaling

Trks are:

a. endonucleases.        b. transmembrane receptors.   c. proteases.     d. protein kinases.      

#Question id: 1397

#Unit 4. Cell Communication and Cell Signaling

The vertebrate equivalent of CED-9 is:

#Question id: 1398

#Unit 4. Cell Communication and Cell Signaling

Which of the following properties is (are) characteristic of a benign tumor?

a. well differentiated              b. localized to tissue of origin             c. metastatic               

d. promotes angiogenesis        e. surrounded by a fibrous capsule

#Question id: 1399

#Unit 4. Cell Communication and Cell Signaling

Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?

a. myc              b. K-ras                       c. p53              d. APC