TLS Online TPP Program
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TLS Online TPP Program
#Question id: 34180
#Unit 3. Fundamental Processes
Many proteins that act at the replication fork interact tightly. Which of the following interactions participate in DNA protein interactions
A. Sequence dependent interaction
B. Negative charge and structure of the phosphate backbone
C. Hydrogen-bonding residues in the minor groove for the palm domain
D. Hydrophobic stacking interactions between the bases for SSBs
Choose true and false
TLS Online TPP Program
#Question id: 34181
#Unit 3. Fundamental Processes
A. In mammalian systems the DNA polymerase does not have a 5’–3’ exonuclease activity
B. In eukaryotes Synthesis of an Okazaki fragment displaces the RNA primer of the preceding fragment in the form of a “flap.”
C. FEN1 functions as an endonuclease and also has a 5’–3’ exonuclease activity
D. FEN1 prevents deletions or duplications in the genome.
Choose true and false
TLS Online TPP Program
#Question id: 34182
#Unit 3. Fundamental Processes
A. The E. coli DNA polymerase III catalytic core contains three subunits, including a catalytic subunit and a proofreading subunit.
B. The DNA Pol III holoenzyme has at least two catalytic cores, a processivity clamp, and a dimerization clamp-loader complex.
C. A clamp loader places the processivity subunits on DNA, where they form a circular clamp around the nucleic acid.
D. Two catalytic core is associated with each template strand.
Which of the following combination is correct
TLS Online TPP Program
#Question id: 34183
#Unit 3. Fundamental Processes
A. A & B can be leading strands
B. B & C can be lagging strands
C. Ligase mutants will affect ether A & D or B & C
D. E and F are origins
E. G is replication fork
Choose true and false
TLS Online TPP Program
#Question id: 34184
#Unit 3. Fundamental Processes
Which of the following is incorrect option
TLS Online TPP Program
#Question id: 34185
#Unit 3. Fundamental Processes
What is the order of proteins from replication fork to origin on leading and lagging strand if
A. helicase B. Primase C. Polymerase