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TLS Online TPP Program

#Question id: 15780

In drosophila, the somatic cells of the hub are able to regulate stem cell proliferation by secreting the paracrine factor Unpaired onto the cells attached to them. Unpaired activates the JAK-STAT pathway in the adjacent germ stem cells to specify their self-renewal. Those cells that are distant from the paracrine factor cannot receive this signal, they begin their differentiation into the sperm cell lineage. This means hub cells act as

#Unit 5. Developmental Biology
  1. Stem cell niches allow controlled self-renewal and also survival of the cells that leave the niche.
  2. Stem cell niches not allow controlled self-renewal but allow survival of the cells that leave the niche.
  3. Stem cell niches allow uncontrolled self-renewal and also division of the cells that leave the niche.
  4. Stem cell niches allow controlled self-renewal and regulate the ratio of cell division to differentiation.
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TLS Online TPP Program

#Question id: 21962

#Unit 2. Cellular Organization

In interphase nuclei, this underlying proteinaceous structure changes its organization to occupy the entire nucleus; during interphase the structure is referred to as the 
TLS Online TPP Program

#Question id: 21963

#Unit 2. Cellular Organization

Which of the following is a DNA sequence which is generally located between H1 and H3 binding sites
TLS Online TPP Program

#Question id: 21964

#Unit 2. Cellular Organization

Choose the incorrect statement 
a. S/MARs are a DNA sequence which is generally located between H1 and H3 binding sites. 
b.  S/MARs are a DNA sequence which is generally located between H3 and H4 binding sites
c. S/MARs is a DNA sequence which binds to base structure called matrix
d.  S/MARs is a DNA sequence which binds to base structure called scaffold
TLS Online TPP Program

#Question id: 21965

#Unit 2. Cellular Organization

Which of the following is a protein that appears to regulate the association of MARs with the matrix in order to regulate transcription of genes in the vicinity of the MAR 
TLS Online TPP Program

#Question id: 21966

#Unit 2. Cellular Organization

Which of the following is true about interphase chromosome
a. Interphase chromosomes occupy chromosome territories in the nucleus
b. Interphase chromosomes occupy chromosome territories toward cell membrane 
c. Interphase chromosomes are not entangled with each other except cancer 
d. Interphase chromosomes are entangled with each other except cancer 
TLS Online TPP Program

#Question id: 21967

#Unit 2. Cellular Organization

Heterochromatic regions, silenced genes, and gene-sparse regions of chromosomes are typically localized to