TLS Online TPP Program

#Question id: 15781


Chemical regulation of stem cells takes the form of secreted proteins from surrounding cells that influence stem cell states and progenitor differentiation through endocrine, paracrine, or juxtacrine mechanisms. These signaling factors:

#Unit 5. Developmental Biology
  1. Maintain the stem cell in an uncommitted state.
  2. Maintain the stem cell in an committed state
  3. Maintain the stem cell in an differentiated state
  4. Maintain the stem cell symmetrical division
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TLS Online TPP Program

#Question id: 7175

#Unit 5. Developmental Biology

The primitive streak is derived from epiblast cells and the central cells of Koller’s sickle. As the primitive streak extends rostrally, Henson’s node is formed. Following are few statements regarding this:

A. As endodermal ingression continues, the primitive streak starts to regress, moving Henson’s node from near the center of the area pellucida to a more posterior position.

B. As endodermal ingression continues, the primitive streak starts to regress, moving Henson’s node from near the periphery of the area pellucida to a more posterior position.

C. As mesodermal ingression continues, the primitive streak starts to regress, moving Henson’s node from near the center of the area pellucida to a more posterior position.

D. As mesodermal ingression continues, the primitive streak starts to regress, moving Henson’s node from near the periphery of the area pellucida to a more anterior position.

Which of the following statements are correct?

TLS Online TPP Program

#Question id: 7176

#Unit 5. Developmental Biology

The metamorphic changes of frog development are brought about by following events.

(A) the secretion of the hormone thyroxine (T4) into the blood by the thyroid gland

(B) the degradation of T3 in the target tissues

(C) the conversion of (T4) into the more active hormone, triiodothyronine (T3) by the target tissues

Which of the following series is correct?

TLS Online TPP Program

#Question id: 7177

#Unit 5. Developmental Biology

Following statements are regarding to the early development in nematodes. Which of the following is incorrect?

TLS Online TPP Program

#Question id: 7178

#Unit 5. Developmental Biology

In sea urchin, the large micromeres are autonomously specified. They inherit maternal determinants that were deposited at the vegetal hemisphere of the egg; these become incorporated into the large micromeres at fourth cleavage. When an isolated animal hemisphere is combined with isolated micromeres, then what will be the result?

TLS Online TPP Program

#Question id: 7179

#Unit 5. Developmental Biology

Blocking BMP(BMP2, BMP4, BMP7) signaling by infecting progress zone cells with retroviruses carrying dominant negative BMP receptors. Which of the following results are found?

TLS Online TPP Program

#Question id: 7180

#Unit 5. Developmental Biology

Development of tetrapod limb has to function in a three dimensional coordinated system:

Proximal-distal axis by ____a_____

Anterior-posterior axis by ___b_____

Dorsal-ventral axis by ______c____

Which of the following combinations are correct?