You and your lab partner have isolated 20 new mutant yeast strains that are defective in synthesis of threonine, an amino acid. These Thr- mutants do not grow on minimal medium, but they do grow on minimal medium supplemented with threonine. Ten of your Thr- mutants (numbered 1 through 10) were isolated in a strain of mating type a (MAT a). The other 10 Thrmutants (numbered 11 through 20) were isolated in a strain of mating type α (MAT α). You and your lab partner cross each of the MAT a strains to each of the MAT α strains, and you include crosses to the appropriate wild-type strains. Your experimental observations are shown in the table below, where (-) indicates diploids that did not grow on minimal medium and (+) indicates diploids that did grow on minimal medium.

Which mutations are dominant?

TLS Online TPP Program

#Question id: 33361

#Unit 1. Molecules and their Interaction Relevant to Biology

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization

b. Hb Milwaukee: substitutes a Glu for a Val

c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer

d. Hb Philly: substitutes a Phe for a Tyr,

Which Hb variant will not bind to BPG

TLS Online TPP Program

#Question id: 33362

#Unit 1. Molecules and their Interaction Relevant to Biology

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization

b. Hb Milwaukee: substitutes a Glu for a Val

c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer

d. Hb Philly: substitutes a Phe for a Tyr

Which Hb variant will have changed pI as compared to HbA

TLS Online TPP Program

#Question id: 33363

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.2

TLS Online TPP Program

#Question id: 33364

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.5

TLS Online TPP Program

#Question id: 33365

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.6

TLS Online TPP Program

#Question id: 33366

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.8