TLS Online TPP Program

#Question id: 15821


Your friends Ben and Jane are contemplating having children and seek your genetic counsel. Ben and Jane are unrelated, but both have younger brothers with the same, extremely rare genetic trait. (In fact, Ben and Jane met at a support group meeting for children and families of children with this rare disorder.) Ben’s parents and Jane’s parents are all unaffected.          
Assume that the trait is autosomal recessive with 80% penetrance. What is the probability that Ben and Jane’s first child will be affected?

#Unit 8. Inheritance Biology
  1. 9/80
  2. 16/20
  3. 5/80
  4. 16/80