TLS Online TPP Program

#Question id: 15834


You are interested in a new type of autosomal dominant mutation that gives purple eyes in Drosophila. You have a true-breeding purple-eyed line carrying a mutation that you call pr-1. You have isolated a second purple-eyed mutation that you call pr-2, which you have established in a true-breeding line that also carries a recessive marker st, which gives stubby legs. You cross a fly from the pr-1 line to a fly from the st, pr-2 line producing F1 females which you then cross to males from a true breeding st line (normal eyes). From this cross, 1000 progeny flies can be categorized into four different phenotypic classes:
                             
Normally, 3-factor crosses give eight different phenotypic classes, why does this particular cross give only four?

#Unit 8. Inheritance Biology
  1. two of the mutations of interest give the same phenotype.
  2. Because the two gene are linked.
  3. Because one of this is double croosover.
  4. two of the mutations of interest shows the different phenotype.