#Question id: 12142
#Unit 10. Ecological Principles
#Question id: 28879
#Unit 4. Cell Communication and Cell Signaling
Wnt signaling receptor is Frizzled (Fz), shows similarity with____
#Question id: 2583
#Unit 2. Cellular Organization
Following statements are regarding to the microtubules.
A. Tubulin is the major structural component of microtubules
B. Microtubule-associated proteins (MAPs) associate with tubulin and help mediate the assembly, dynamics, and function of microtubules.
C. Free tubulin exists as a dimer in which the α-subunit contains a trapped and hydrolyzable GTP and theβ-subunit binds an exchangeable and nonhydrolyzable GTP
D. All microtubules are nucleated from microtubule-organizing centers (MTOCs), and many remain anchored with their (−) ends there. Thus the end away from the MTOC is always the (+) end.
Which of the following statements is incorrect?
#Question id: 12136
#Unit 10. Ecological Principles
#Question id: 4110
#Unit 3. Fundamental Processes
Tay-Sachs disease belongs to the family of lysosomal storage diseases; it is an autosomal recessive neurodegenerative disorder caused by deficiency of the lysosomal enzyme hexosaminidase. The inability to degrade sphingolipids results in the deposition of these lipids in the cells that causes severe mental retardation and death in childhood. The most common mutation in Tay-Sachs disease patients is a 4-base pair insertion in exon 11 of the 14 exons of the hexosaminidase gene. What could be the most likely consequence of this mutation?