Practice Questions

TLS Online TPP Program

#Question id: 1439

Indirect-acting carcinogens are those that:

#Unit 4. Cell Communication and Cell Signaling

chemically react with nitrogen and oxygen atoms in DNA.
can modify bases in DNA so as to distort the normal pattern of base pairing.
are mainly reactive electrophiles.
generally unreactive, often water-insoluble compounds that can act as potent cancer inducers only after the introduction of electrophilic centers.

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TLS Online TPP Program

#Question id: 15841

#Unit 8. Inheritance Biology

In the yeast cross of ade2 met14 his3 x + + +, a total of 120 tetrads are analyzed. The following tetrad types are found in the numbers shown below each tetrad. The markers ade2, met14, and his3 are abbreviated a, m, and h and the wild type allele of each gene is indicated by +.

Based on your numbers, calculate the distance between his2 and his4.

TLS Online TPP Program

#Question id: 15842

#Unit 8. Inheritance Biology

In the yeast cross of ade2 met14 his3 x + + +, a total of 120 tetrads are analyzed. The markers ade2, met14, and his3 are abbreviated a, m, and h and the wild type allele of each gene is indicated by +.

Given three locus from above, which locus shows the tetratype (T)

TLS Online TPP Program

#Question id: 15843

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml. What is the distance between the ts-1 and ts-2 mutations in m.u.?

TLS Online TPP Program

#Question id: 15844

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts^-1 to ts^-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml.

If the total size of the phage is 5 x 10⁴ bp and the total genetic map length of the phage is 100 m.u., about how far apart are the mutations in base pairs?

TLS Online TPP Program

#Question id: 15845

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml. Find out the relative order of sm, ts-1 and ts-2?

TLS Online TPP Program

#Question id: 15846

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml. the relative order is sm→ts-2→ts-1, find out the distances you can calculate in m.u.?