TLS Online TPP Program

#Question id: 16122


Fever is an abnormal elevation of body temperature. Following statements are regarding to the cellular mechanism of fever.
A. Pyrogens produce fever by increasing the hypothalamic set-point temperature.
B. the mechanism of pyrogen action is increased production of interleukin-1 (IL-1) in phagocytic cells.
C. IL-1 then acts on the anterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.
D. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.
E. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which decrease the set-point temperature.
Which of the following combination is correct?

#Unit 7. System Physiology – Animal
  1. A & B only
  2. A, B & C
  3. A, B & D
  4. A, B & E