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TLS Online TPP Program

#Question id: 16148

 Which statement is not true for NKT Cells?

#Unit 4. Cell Communication and Cell Signaling
  1. NKT cells, have received a great deal of recent attention and share features with both conventional T lymphocytes and NK cells.
  2. Like T cells, NKT cells have T-cell receptors (TCRs), and some express CD4. Unlike most T cells, however, the TCRs of NKT cells are not very diverse and recognize specific lipids and glycolipids presented by a molecule related to MHC proteins known as CD1.
  3. Like their innate immune relatives, NK cells, NKT cells have antibody receptors, as well as other receptors classically associated with NK cells. Activated NKT cells can release cytotoxic granules that kill target cells.
  4. they can not also release large quantities of cytokines that can both enhance and suppress the immune response. They appear to be involved in human asthma, but also may inhibit the development of autoimmunity and cancer
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TLS Online TPP Program

#Question id: 4399

#Unit 3. Fundamental Processes

Transcription factors can

a. exhibit cooperative binding.  b. exist as heterodimers.

c. act to repress transcription of transcription factor genes.

d. undergo conformational changes which alter activity.

e. never interact with co-repressors.
TLS Online TPP Program

#Question id: 4400

#Unit 3. Fundamental Processes

Which is the first factor to bind at the promoter of eukaryotic genes?

a. RNA polymerase

b. TFIIA

c. TFIIB

d. TFIID 

e. TATA box–binding protein
TLS Online TPP Program

#Question id: 4401

#Unit 3. Fundamental Processes

Which of the following occur(s) during Pol II transcription preinitiation complex formation?

a. TFIIA binds to TFIIB.  b. TFIIB unwinds the DNA.

c. TFIIB contacts both TATA box–binding factor and DNA.

d. DNA bends.
TLS Online TPP Program

#Question id: 4402

#Unit 3. Fundamental Processes

Chromatin-mediated repression of transcription involves

a. modification of lysine residues in histones. 

b. large, multiprotein complexes.

c. acetylation of histone tails.   

d. deacetylation of histone tails.
TLS Online TPP Program

#Question id: 4403

#Unit 3. Fundamental Processes

 Which of the following does (do) not require a DNA helicase activity?

a. SWI/SNF function  b. Pol II open-complex formation

c. transcription-factor binding to DNA

d. deacetylation of histone tails
TLS Online TPP Program

#Question id: 4404

#Unit 3. Fundamental Processes

The yeast two-hybrid system can be used to identify

a. proteins that interact with a known or “bait” protein.

b. proteins that interact with a “fish” domain.

c. cDNAs that encode interacting proteins.

d. co-activators and co-repressors.