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TLS Online TPP Program
#Question id: 15302
#Unit 5. Developmental Biology
FOXP1 is a transcription factor which stimulate the production of Oct4 and Nanog and establish pluripotency. Which of the following statements are correct regarding to the mechanism of alternative splicing of FOXP1.
A. There are two isoforms of the FoxP1 protein, One is the product of an mRNA spliced to include a particular exon, 18b, while the other splicing variant carries exon 18a.
B. When alternative splicing generates a form including exon 18b in place of 18a, the resulting isoform (FOXP1-ES) binds to a different DNA sequence and thus controls expression of a different set of genes.
C. The protein encoded by the exon 18b– carrying mRNA is called FOXP1-ES it fails to stimulate expression of OCT4 and NANOG and instead actives genes that promote differentiation.
D. The exon 18a– containing form encodes FOXP1 itself, and this has the opposite effect: this activates genes that promote dedifferentiation, and thus stimulates iPS cell formation.
TLS Online TPP Program
#Question id: 12671
#Unit 6. System Physiology – Plant
When genetic changes in an entire plant population have been fixed over many generations by selective environmental pressure, those changes are referred to as,
TLS Online TPP Program
#Question id: 3676
#Unit 3. Fundamental Processes
Which function can be carried out by DNA replication proteins?
TLS Online TPP Program
#Question id: 31018
#Unit 4. Cell Communication and Cell Signaling
Same ligand can induce different cells to respond in a variety of ways, often in a manner that coordinates the overall response of the organism. This property is known as:
TLS Online TPP Program
#Question id: 12452
#Unit 10. Ecological Principles
Butterflies are used as an example of a species with