A research team is working on the design of a new drug for the treatment of lung cancer. To be most effective, this drug must specifically enter the cytoplasm of lung cells while not entering the cells of other tissues. Which of the following characteristics would likely enhance the specificity of this drug?

TLS Online TPP Program

#Question id: 28062

#Unit 1. Molecules and their Interaction Relevant to Biology

Thermostable proteins are stable at high temperature due to

a. Vander Waals interaction

b. Ionic bond only

c. High protein’s hydrophobic core 

d. high incidence of salt bridges

Which of the following is correct 

TLS Online TPP Program

#Question id: 28063

#Unit 1. Molecules and their Interaction Relevant to Biology

Characteristics of Thermostable proteins are  

a. loosely packed core as evidenced by a high surface-to-volume ratio.

b. High amounts of Arg

c. High amount of Ala in helices

d. Stable at high temperature due to High protein’s hydrophobic core and high incidence of salt bridges

TLS Online TPP Program

#Question id: 28064

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following Techniques can be used to for Measuring Stability of protein    

a. DSC (calorimetry) 

b. Urea gradient gels 

c. FRET

d. EPR

Which of the following is correct

TLS Online TPP Program

#Question id: 28065

#Unit 1. Molecules and their Interaction Relevant to Biology

Guanidinium ion and urea are  

TLS Online TPP Program

#Question id: 28066

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following parameter is measured during analysis for the Stability of protein by DSC (calorimetry) 

TLS Online TPP Program

#Question id: 28067

#Unit 1. Molecules and their Interaction Relevant to Biology

The graph shown below is for Fluorescence emission spectra any protein X, The which of the following assumption can be made