Tumor-suppressor genes generally encode proteins that in one way or another inhibit cell proliferation. Loss-of-function mutations in one or more of these proliferation inhibitory proteins contribute to the development of many cancers. Prominent among the classes of proteins encoded by tumor-suppressor genes are:

A. Intracellular proteins that regulate or inhibit entry into the cell cycle

B. Receptors or signal transducers for secreted hormones or developmental signals that inhibit cell proliferation

C. Checkpoint pathway proteins that arrest the cell cycle if DNA is damaged

D. Proteins that promote apoptosis

Following genes belongs to the above class-

i. p53

ii. Rb

iii.TGF- β

iv. Caspase 3 and 7

which of the following match is correct?

TLS Online TPP Program

#Question id: 14839

#Unit 5. Developmental Biology

Given are certain facts which define ‘specification’ of a developing embryo.

 A. At the specification stage, commitment to cell identity is labile.

 B. At the specification stage, cell is capable of differentiating autonomously.

 C. The cell “knows” very early what it is to become without interacting with other cells.

 D. A phase where inductive signals trigger cell to determines their fate.

 Which of the above statements best define specification?

TLS Online TPP Program

#Question id: 14840

#Unit 5. Developmental Biology

If a cell or tissue type is able to differentiate according to its specified fate, it is assumed that commitment is:

TLS Online TPP Program

#Question id: 14841

#Unit 5. Developmental Biology

How cells became different from one another during embryonic development?

TLS Online TPP Program

#Question id: 14842

#Unit 5. Developmental Biology

If a specified cell is transplanted to a population of differently specified cells, the fate of the transplant will be:

A. Altered if the specification is reversible

B. Capable of differentiating by itself if the specification is reversible

C. Altered if the specification is irreversible

D. Capable of differentiating by itself if the specification is irreversible

Which of the following combination is correct?

TLS Online TPP Program

#Question id: 14843

#Unit 5. Developmental Biology

In both animals and plants, undifferentiated cells go through a process of maturation that begins when they become committed to a specific cell lineage.

   

Which of the following option represents correct events regarding to series

TLS Online TPP Program

#Question id: 14844

#Unit 13. Methods in Biology

An urn contains 25 balls numbered 1 through 25. Two balls are drawn from the urn with replacement. The probability of getting at least one odd is