TLS Online TPP Program

#Question id: 1525


Following statements are regarding to chromatin remodelling factors SWI/SNF complexes. Which one of them is incorrect?

#Unit 4. Cell Communication and Cell Signaling
  1. SWI/SNF complexes large and diverse multiprotein complexes, which have an ATP-dependent helicase at their core, often control histone modification and chromatin remodeling.

  2. SWI/SNF complexes can cause changes in the positions or structures of nucleosomes, making genes accessible or inaccessible to DNA-binding proteins that control transcription.

  3. SWI/SNF plays a role in repressing the expression of E2F genes, thereby inhibiting progression through the cell cycle.

  4. Loss of SWI/SNF function, just like gain of Rb function, can lead to overgrowth and tumor formation.